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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HCFC1 All Species: 23.33
Human Site: T1752 Identified Species: 46.67
UniProt: P51610 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51610 NP_005325.2 2035 208732 T1752 A L L P S T A T E S L A P S N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001088011 1702 173511 T1326 C S N P P C E T H E T G T T H
Dog Lupus familis XP_867443 2039 208943 T1756 A L L P S T G T E S L A P S N
Cat Felis silvestris
Mouse Mus musculus Q61191 2045 210519 T1763 A L L P S T A T E S L A P S N
Rat Rattus norvegicus Q5RKG2 723 79130 G447 H T A V A A R G M S L K S K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509058 2033 207643 T1750 A L L P S T A T E S L A P S S
Chicken Gallus gallus XP_001234928 787 86020 S511 V I P D A S V S S T V S S T Q
Frog Xenopus laevis NP_001087989 2101 219049 T1823 A L L P T T A T D N L T V S N
Zebra Danio Brachydanio rerio Q7ZUV7 1173 122182 S897 Q T G L F Y R S S P Q Q Q L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4C8 1500 160166 R1224 A L K E L I E R P E S E T N T
Honey Bee Apis mellifera XP_624189 1550 166762 T1274 E Q M N G T R T E N G D D S T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791039 1216 126587 D940 G I P A E P T D T T K T N G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 82.3 93.8 N.A. 93.7 24.2 N.A. 82.4 26.3 68.8 20.4 N.A. 33 34.2 N.A. 37
Protein Similarity: 100 N.A. 82.5 95 N.A. 95.5 30 N.A. 86 32.2 76.6 33.1 N.A. 47.5 50.2 N.A. 46.5
P-Site Identity: 100 N.A. 13.3 93.3 N.A. 100 13.3 N.A. 93.3 0 66.6 0 N.A. 13.3 26.6 N.A. 0
P-Site Similarity: 100 N.A. 26.6 93.3 N.A. 100 20 N.A. 100 53.3 86.6 13.3 N.A. 20 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 9 9 17 9 34 0 0 0 0 34 0 0 0 % A
% Cys: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 9 0 0 9 9 0 0 % D
% Glu: 9 0 0 9 9 0 17 0 42 17 0 9 0 0 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 9 0 9 9 0 0 9 9 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 9 0 0 0 0 0 0 0 9 9 0 9 0 % K
% Leu: 0 50 42 9 9 0 0 0 0 0 50 0 0 9 0 % L
% Met: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 9 0 0 0 0 0 17 0 0 9 9 34 % N
% Pro: 0 0 17 50 9 9 0 0 9 9 0 0 34 0 9 % P
% Gln: 9 9 0 0 0 0 0 0 0 0 9 9 9 0 9 % Q
% Arg: 0 0 0 0 0 0 25 9 0 0 0 0 0 0 0 % R
% Ser: 0 9 0 0 34 9 0 17 17 42 9 9 17 50 25 % S
% Thr: 0 17 0 0 9 50 9 59 9 17 9 17 17 17 17 % T
% Val: 9 0 0 9 0 0 9 0 0 0 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _